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Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo
T cells primed in the gut-draining mesenteric lymph nodes (mLN) are imprinted to express α4β7-integrin and chemokine receptor CCR9, thereby enabling lymphocytes to migrate to the small intestine. In vitro activation by intestinal dendritic cells (DC) or addition of retinoic acid (RA) is sufficient t...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571923/ https://ncbi.nlm.nih.gov/pubmed/18852290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080039 |
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