CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

Immune mechanisms are known to control the pathogenesis of atherosclerosis. However, the exact role of DCs, which are essential for priming of immune responses, remains elusive. We have shown here that the DC-derived chemokine CCL17 is present in advanced human and mouse atherosclerosis and that CCL...

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Главные авторы: Weber, Christian, Meiler, Svenja, Döring, Yvonne, Koch, Miriam, Drechsler, Maik, Megens, Remco T.A., Rowinska, Zuzanna, Bidzhekov, Kiril, Fecher, Caroline, Ribechini, Eliana, van Zandvoort, Marc A.M.J., Binder, Christoph J., Jelinek, Ivett, Hristov, Mihail, Boon, Louis, Jung, Steffen, Korn, Thomas, Lutz, Manfred B., Förster, Irmgard, Zenke, Martin, Hieronymus, Thomas, Junt, Tobias, Zernecke, Alma
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223829/
https://ncbi.nlm.nih.gov/pubmed/21633167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44925
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