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CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

Immune mechanisms are known to control the pathogenesis of atherosclerosis. However, the exact role of DCs, which are essential for priming of immune responses, remains elusive. We have shown here that the DC-derived chemokine CCL17 is present in advanced human and mouse atherosclerosis and that CCL...

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Detalhes bibliográficos
Main Authors: Weber, Christian, Meiler, Svenja, Döring, Yvonne, Koch, Miriam, Drechsler, Maik, Megens, Remco T.A., Rowinska, Zuzanna, Bidzhekov, Kiril, Fecher, Caroline, Ribechini, Eliana, van Zandvoort, Marc A.M.J., Binder, Christoph J., Jelinek, Ivett, Hristov, Mihail, Boon, Louis, Jung, Steffen, Korn, Thomas, Lutz, Manfred B., Förster, Irmgard, Zenke, Martin, Hieronymus, Thomas, Junt, Tobias, Zernecke, Alma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223829/
https://ncbi.nlm.nih.gov/pubmed/21633167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44925
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