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S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy
Rapamycin is an antibiotic inhibiting eukaryotic cell growth and proliferation by acting on target of rapamycin (TOR) kinase. Mammalian TOR (mTOR) is thought to work through 2 independent complexes to regulate cell size and cell replication, and these 2 complexes show differential sensitivity to rap...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223822/ https://ncbi.nlm.nih.gov/pubmed/21633171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44203 |
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