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S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy

Rapamycin is an antibiotic inhibiting eukaryotic cell growth and proliferation by acting on target of rapamycin (TOR) kinase. Mammalian TOR (mTOR) is thought to work through 2 independent complexes to regulate cell size and cell replication, and these 2 complexes show differential sensitivity to rap...

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Autors principals: Espeillac, Catherine, Mitchell, Claudia, Celton-Morizur, Séverine, Chauvin, Céline, Koka, Vonda, Gillet, Cynthia, Albrecht, Jeffrey H., Desdouets, Chantal, Pende, Mario
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223822/
https://ncbi.nlm.nih.gov/pubmed/21633171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44203
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