Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: Is that a latent disadvantage?

BACKGROUND: Fenofibrate, a PPAR alpha agonist, has been widely used in clinics as lipid-regulating agent. PPAR alpha is known to be expressed in many organs including pancreatic beta cells and regulate genes involved in fatty acid metabolism. Some reports based on cell lines or animals have provided...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Shuai-nan, Liu, Quan, Li, Lin-yi, Huan, Yi, Sun, Su-juan, Shen, Zhu-fang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223503/
https://ncbi.nlm.nih.gov/pubmed/21999347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-176
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados