Diphenyleneiodonium inhibits NF-kappaB activation and iNOS expression induced by IL-1beta: involvement of reactive oxygen species.

AIMS: In this work, we studied the mechanisms by which diphenyleneiodonium chloride (DPI) inhibits nitric oxide (NO) synthesis induced by the proinflammatory cytokine interleukin-1beta (IL-1) in bovine articular chondrocytes. To achieve this, we evaluated the ability of DPI to inhibit the expression...

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Main Authors: Mendes, A F, Carvalho, A P, Caramona, M M, Lopes, M C
格式: Artigo
語言:Inglês
出版: 2001
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781711/
https://ncbi.nlm.nih.gov/pubmed/11577997
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