State-of-the-Art Automated Patch Clamp Devices: Heat Activation, Action Potentials, and High Throughput in Ion Channel Screening

Ion channels are essential in a wide range of cellular functions and their malfunction underlies many disease states making them important targets in drug discovery. The availability of standardized cell lines expressing ion channels of interest lead to the development of diverse automated patch cla...

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Detalhes bibliográficos
Main Authors: Stoelzle, Sonja, Obergrussberger, Alison, Brüggemann, Andrea, Haarmann, Claudia, George, Michael, Kettenhofen, Ralf, Fertig, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223389/
https://ncbi.nlm.nih.gov/pubmed/22131976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00076
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