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Modeling the pharmacodynamics of passive membrane permeability
Small molecule permeability through cellular membranes is critical to a better understanding of pharmacodynamics and the drug discovery endeavor. Such permeability may be estimated as a function of the free energy change of barrier crossing by invoking the barrier domain model, which posits that per...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223344/ https://ncbi.nlm.nih.gov/pubmed/22042376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-011-9480-7 |
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