Enhanced Hsp70 Expression Protects against Acute Lung Injury by Modulating Apoptotic Pathways

The Acute respiratory distress syndrome (ARDS) is a highly lethal inflammatory lung disorder. Apoptosis plays a key role in its pathogenesis. We showed that an adenovirus expressing the 70 kDa heat shock protein Hsp70 (AdHSP) protected against sepsis-induced lung injury. In this study we tested the...

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Main Authors: Aschkenasy, Gabriella, Bromberg, Zohar, Raj, Nichelle, Deutschman, Clifford S., Weiss, Yoram G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223157/
https://ncbi.nlm.nih.gov/pubmed/22132083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026956
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