RAD51 can inhibit PDGF-B–induced gliomagenesis and genomic instability

Faithful replication and DNA repair are vital for maintenance of genome integrity. RAD51 is a central protein in homologous recombination repair and during replication, when it protects and restarts stalled replication forks. Aberrant RAD51 expression occurs in glioma, and high expression has been s...

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Dades bibliogràfiques
Autors principals: Westermark, Ulrica K., Lindberg, Nanna, Roswall, Pernilla, Bråsäter, Daniel, Helgadottir, Hildur R., Hede, Sanna-Maria, Zetterberg, Anders, Jasin, Maria, Nistér, Monica, Uhrbom, Lene
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223091/
https://ncbi.nlm.nih.gov/pubmed/21926087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor131
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