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The Activation Cycle of Rab GTPase Ypt32 Reveals Structural Determinants of Effector Recruitment and GDI binding
Rab GTPases localize to distinct sub-cellular compartments and regulate vesicle trafficking in eukaryotic cells. Yeast Rabs Ypt31/32 and Sec4 have 68% homology and bind to common interactors, yet play distinct roles in the transport of exocytic vesicles. The structures of Ypt31/32 have not previousl...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222890/ https://ncbi.nlm.nih.gov/pubmed/22024479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.10.013 |
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