NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

The histone lysine methyltransferase NSD2 (MMSET/WHSC1) is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in understanding how this enz...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kuo, Alex J., Cheung, Peggie, Chen, Kaifu, Zee, Barry M., Kioi, Mitomu, Lauring, Josh, Xi, Yuanxin, Park, Ben Ho, Shi, Xiaobing, Garcia, Benjamin A., Li, Wei, Gozani, Or
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222870/
https://ncbi.nlm.nih.gov/pubmed/22099308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.042
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky