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Inhibitory Actions of HERG Currents by the Immunosuppressant Drug Cyclosporin A
The effect of cyclosporin A (CsA), an immunosuppressant, on human ether-a-go-go-related gene (HERG) channel as it is expressed in human embryonic kidney cells was studied using a whole-cell, patch-clamp technique. CsA inhibited the HERG channel in a concentration-dependent manner, with an IC(50) val...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222799/ https://ncbi.nlm.nih.gov/pubmed/22128262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2011.15.5.291 |
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