Testing the white matter retrogenesis hypothesis of cognitive aging

BACKGROUND: The retrogenesis hypothesis postulates that late-myelinated white matter fibers are most vulnerable to age- and disease-related degeneration, which in turn mediate cognitive decline. While recent evidence supports this hypothesis in the context of Alzheimer’s disease, it has not been tes...

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Main Authors: Brickman, Adam M., Meier, Irene B., Korgaonkar, Mayuresh S., Provenzano, Frank A., Grieve, Stuart M., Siedlecki, Karen L., Wasserman, Ben T., Williams, Leanne M., Zimmerman, Molly E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222729/
https://ncbi.nlm.nih.gov/pubmed/21783280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.06.001
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