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New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials

Since it has been established that the injection of plasmid DNA can lead to an efficient expression of a specific protein in vivo, nonviral gene therapy approaches have been considerably improved, allowing clinical trials. However, the use of antibiotic resistance genes as selection markers for plas...

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Detalhes bibliográficos
Main Authors: Vandermeulen, Gaëlle, Marie, Corinne, Scherman, Daniel, Préat, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222533/
https://ncbi.nlm.nih.gov/pubmed/21878901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.182
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