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New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials

Since it has been established that the injection of plasmid DNA can lead to an efficient expression of a specific protein in vivo, nonviral gene therapy approaches have been considerably improved, allowing clinical trials. However, the use of antibiotic resistance genes as selection markers for plas...

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Bibliografiske detaljer
Main Authors: Vandermeulen, Gaëlle, Marie, Corinne, Scherman, Daniel, Préat, Véronique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222533/
https://ncbi.nlm.nih.gov/pubmed/21878901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.182
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