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Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target
Pediatric high-grade gliomas (World Health Organization grades III and IV astrocytomas) remain tumors with a very poor prognosis for which novel therapeutic strategies are needed. Poly(ADP-ribose) polymerase (PARP) is known to have multiple functions in tumors, including single-strand DNA repair and...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222516/ https://ncbi.nlm.nih.gov/pubmed/21849329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor115 |
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