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The role of JAK2 abnormalities in hematologic neoplasms

In 2005, an activating mutation in the Janus kinase 2 (JAK2) was identified in a significant proportion of patients with myeloproliferative neoplasms, mainly polycythemia vera, essential thrombocythemia and primary myelofibrosis. Many types of mutations in the JAK-STAT pathway have been identified,...

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Autore principale: Alabdulaali, Mohammed K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: PAGEPress Publications 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222247/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2009.e10
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