Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain

Complex cellular functions involve large networks of interactions. Pre-mRNA splicing and transcription are thought to be coupled by the C-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II). In yeast, the U1 snRNP subunit Prp40 was proposed to mediate cotranscriptional recruitme...

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Main Authors: Görnemann, Janina, Barrandon, Charlotte, Hujer, Katja, Rutz, Berthold, Rigaut, Guillaume, Kotovic, Kimberly M., Faux, Céline, Neugebauer, Karla M., Séraphin, Bertrand
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222125/
https://ncbi.nlm.nih.gov/pubmed/22020974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.02646811
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