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Spectroscopic and Electronic Structure Studies Probing Covalency Contributions to C-H Bond Activation and Transition State Stabilization in Xanthine Oxidase

A detailed EPR and computational study of a key paramagnetic form of xanthine oxidase (XO) has been performed which serves as a basis for developing a valence bond description of C-H activation and transition state stabilization along the reaction coordinate with aldehyde substrates. EPR spectra of...

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Bibliographic Details
Main Authors: Sempombe, Joseph, Stein, Benjamin, Kirk, Martin L.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222092/
https://ncbi.nlm.nih.gov/pubmed/21972782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ic201477n
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