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Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity

Prothrombin complex concentrates (PCCs) are used mainly for emergency reversal of vitamin K antagonist therapy. Historically, the major drawback with PCCs has been the risk of thrombotic complications. The aims of the present review are to examine thrombotic complications reported with PCCs, and to...

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Bibliografiske detaljer
Main Authors: Sørensen, Benny, Spahn, Donat R, Innerhofer, Petra, Spannagl, Michael, Rossaint, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222012/
https://ncbi.nlm.nih.gov/pubmed/21345266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9311
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