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Molecular beacon-based tricomponent probe for SNP analysis in folded nucleic acids
Hybridization probes are often inefficient in the analysis of single-stranded DNA or RNA that are folded in stable secondary structures. An MB probe is a short DNA hairpin with a fluorophore and a quencher attached to the opposite sides of the oligonucleotide. The probe is widely used in real-time a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221966/ https://ncbi.nlm.nih.gov/pubmed/21956816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201101987 |
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