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Molecular beacon-based tricomponent probe for SNP analysis in folded nucleic acids

Hybridization probes are often inefficient in the analysis of single-stranded DNA or RNA that are folded in stable secondary structures. An MB probe is a short DNA hairpin with a fluorophore and a quencher attached to the opposite sides of the oligonucleotide. The probe is widely used in real-time a...

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Detalhes bibliográficos
Main Authors: Nguyen, Camha, Grimes, Jeffrey, Gerasimova, Yulia V., Kolpashchikov, Dmitry M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221966/
https://ncbi.nlm.nih.gov/pubmed/21956816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201101987
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