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Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous manifestations including severe organ damage and vascular dysfunction leading to premature atherosclerosis. Interferon-alpha (IFN-α) has been proposed to have an important role in the development of lupus and lupus-relate...

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Autors principals: Kahlenberg, J. Michelle, Thacker, Seth G., Berthier, Celine C., Cohen, Clemens D., Kretzler, Matthias, Kaplan, Mariana J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221936/
https://ncbi.nlm.nih.gov/pubmed/22058412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101284
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