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Synthetic scaffold coating with adeno-associated virus encoding BMP2 to promote endogenous bone repair

Biomaterial scaffolds functionalized to stimulate endogenous repair mechanisms via the incorporation of osteogenic cues offer a potential alternative to bone grafting for the treatment of large bone defects. We first quantified the ability of a self-complementary adeno-associated viral vector encodi...

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Autors principals: Dupont, Kenneth M., Boerckel, Joel D., Stevens, Hazel Y., Diab, Tamim, Kolambkar, Yash M., Takahata, Masahiko, Schwarz, Edward M., Guldberg, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221920/
https://ncbi.nlm.nih.gov/pubmed/21695398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-011-1197-3
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