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Three-Dimensional Cancer-Bone Metastasis Model Using Ex-Vivo Co-Cultures of Live Calvarial Bones and Cancer Cells

One of the major limitations of studying cancer-bone metastasis has been the lack of an appropriate ex-vivo model which can be used under defined conditions that simulates closely the in vivo live bone microenvironment in response to cancer-bone interactions. We have developed and utilized a three-d...

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Bibliografiske detaljer
Main Authors: Curtin, Paul, Youm, Helen, Salih, Erdjan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221840/
https://ncbi.nlm.nih.gov/pubmed/22071100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.10.046
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