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PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase
Efficient clearance of apoptotic cells by phagocytes (efferocytosis) is critical for normal tissue homeostasis and regulation of immune system. Apoptotic cells are recognized by a vast repertoire of receptors on macrophage that lead to transient formation of phosphatidylinositol-3,4,5-trisphosphate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221816/ https://ncbi.nlm.nih.gov/pubmed/22043008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100484 |
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