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Influenza Virus Pathophysiology and Brain Invasion in Mice with Functional and Dysfunctional Mx1 Genes

Mice with a dysfunctional myxovirus resistance-1 (dMx1) gene transport intranasally-instilled PR8 influenza virus to the olfactory bulb (OB) within 4 h post-infection. To determine if the presence of a functional Mx1 (fMx1) gene would influence this brain viral localization and/or disease, we infect...

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Detalhes bibliográficos
Main Authors: Hodgson, Nicole R., Bohnet, Stewart G., Majde, Jeannine A., Krueger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221813/
https://ncbi.nlm.nih.gov/pubmed/21821116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2011.07.238
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