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Calcium/calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis

Renal involvement in systemic lupus erythematosus (SLE) remains a major cause of morbidity and mortality. Although immune parameters that instigate renal damage have been characterized, their link to local processes, which execute tissue damage, is poorly understood. Using genetic deletion and pharm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ichinose, Kunihiro, Rauen, Thomas, Juang, Yuang-Taung, Kis-Toth, Katalin, Mizui, Masayuki, Koga, Tomohiro, Tsokos, George C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221799/
https://ncbi.nlm.nih.gov/pubmed/22031763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102357
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