Pathophysiology of Huntington’s Disease: Time-Dependent Alterations in Synaptic and Receptor Function

Huntington’s disease (HD) is a progressive, fatal neurological condition caused by an expansion of CAG (glutamine) repeats in the coding region of the Huntington gene. To date, there is no cure but great strides have been made to understand pathophysiological mechanisms. In particular, genetic anima...

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Autors principals: Raymond, Lynn A., André, Véronique M., Cepeda, Carlos, Gladding, Clare M., Milnerwood, Austen J., Levine, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221774/
https://ncbi.nlm.nih.gov/pubmed/21907762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.08.052
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