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The Role of the Novel Exopolyphosphatase MT0516 in Mycobacterium tuberculosis Drug Tolerance and Persistence

Inorganic polyphosphate (poly P) has been postulated to play a regulatory role in the transition to bacterial persistence. In bacteria, poly P balance in the cell is maintained by the hydrolysis activity of the exopolyphosphatase PPX. However, the Mycobacterium tuberculosis PPX has not been characte...

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Autors principals: Thayil, Seema M., Morrison, Norman, Schechter, Norman, Rubin, Harvey, Karakousis, Petros C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221697/
https://ncbi.nlm.nih.gov/pubmed/22132215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028076
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