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The Anticancer Plant Triterpenoid, Avicin D, Regulates Glucocorticoid Receptor Signaling: Implications for Cellular Metabolism

Avicins, a family of apoptotic triterpene electrophiles, are known to regulate cellular metabolism and energy homeostasis, by targeting the mitochondria. Having evolved from “ancient hopanoids,” avicins bear a structural resemblance with glucocorticoids (GCs), which are the endogenous regulators of...

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Main Authors: Haridas, Valsala, Xu, Zhi-Xiang, Kitchen, Doug, Jiang, Anna, Michels, Peter, Gutterman, Jordan U.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221683/
https://ncbi.nlm.nih.gov/pubmed/22132201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028037
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