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Avicin D, a Plant Triterpenoid, Induces Cell Apoptosis by Recruitment of Fas and Downstream Signaling Molecules into Lipid Rafts

Avicins, a family of triterpene electrophiles originally identified as potent inhibitors of tumor cell growth, have been shown to be pleiotropic compounds that also possess antioxidant, anti-mutagenic, and anti-inflammatory activities. We previously showed that Jurkat cells, which express a high lev...

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Autori principali: Xu, Zhi-Xiang, Ding, Tian, Haridas, Valsala, Connolly, Fiona, Gutterman, Jordan U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797328/
https://ncbi.nlm.nih.gov/pubmed/20046832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008532
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