Polymorphisms in Genes Involved in the NF-κB Signalling Pathway Are Associated with Bone Mineral Density, Geometry and Turnover in Men

INTRODUCTION: In this study, we aimed to investigate the association between single nucleotide polymorphisms (SNPs) within two genes involved in the NF-κB cascade (GPR177 and MAP3K14) and bone mineral density (BMD) assessed at different skeletal sites, radial geometric parameters and bone turnover....

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Main Authors: Roshandel, Delnaz, Thomson, Wendy, Pye, Stephen R., Boonen, Steven, Borghs, Herman, Vanderschueren, Dirk, Huhtaniemi, Ilpo T., Adams, Judith E., Ward, Kate A., Bartfai, Gyorgy, Casanueva, Felipe F., Finn, Joseph D., Forti, Gianni, Giwercman, Aleksander, Han, Thang S., Kula, Krzysztof, Lean, Michael E., Pendleton, Neil, Punab, Margus, Wu, Frederick C., Holliday, Kate L., O'Neill, Terence W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221678/
https://ncbi.nlm.nih.gov/pubmed/22132199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028031
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