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Activation of Ras Requires the ERM-Dependent Link of Actin to the Plasma Membrane
BACKGROUND: Receptor tyrosine kinases (RTKs) participate in a multitude of signaling pathways, some of them via the small G-protein Ras. An important component in the activation of Ras is Son of sevenless (SOS), which catalyzes the nucleotide exchange on Ras. PRINCIPAL FINDINGS: We can now demonstra...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221661/ https://ncbi.nlm.nih.gov/pubmed/22132106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027511 |
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