Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility

Reproduction in mammals is dependent on the function of specific neurons that secrete gonadotropin-releasing hormone-1 (GnRH-1). These neurons originate prenatally in the nasal placode and migrate into the forebrain along the olfactory–vomeronasal nerves. Alterations in this migratory process lead t...

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Autori principali: Messina, Andrea, Ferraris, Nicoletta, Wray, Susan, Cagnoni, Gabriella, Donohue, Duncan E., Casoni, Filippo, Kramer, Phillip R., Derijck, Alwin A., Adolfs, Youri, Fasolo, Aldo, Pasterkamp, Ronald J., Giacobini, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221532/
https://ncbi.nlm.nih.gov/pubmed/21903667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr403
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