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ASIC-like Currents in Freshly Isolated Cerebral Artery Smooth Muscle Cells are Inhibited by Endogenous Oxidase Activity

Background/Aims: The aim of this study was to determine if VSMC ASIC-like currents are regulated by oxidative state. Methods: We used whole-cell patch clamp of isolated mouse cerebral VSMCs to determine if 1) reducing agents, such as DTT and GSH, and 2) inhibition of endogenous oxidase activity from...

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Detalhes bibliográficos
Main Authors: Chung, Wen-Shuo, Farley, Jerry M., Drummond, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221264/
https://ncbi.nlm.nih.gov/pubmed/21325830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000325215
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