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Rosuvastatin does not affect human apolipoprotein A-I expression in genetically modified mice: a clue to the disputed effect of statins on HDL

BACKGROUND AND PURPOSE: Besides a significant reduction of low-density lipoprotein (LDL) cholesterol, statins moderately increase high-density lipoprotein (HDL) levels. In vitro studies have indicated that this effect may be the result of an increased expression of apolipoprotein (apo)A-I, the main...

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Detalhes bibliográficos
Main Authors: Marchesi, Marta, Parolini, Cinzia, Caligari, Silvia, Gilio, Donatella, Manzini, Stefano, Busnelli, Marco, Cinquanta, Paola, Camera, Marina, Brambilla, Marta, Sirtori, Cesare R, Chiesa, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221100/
https://ncbi.nlm.nih.gov/pubmed/21486287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01429.x
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