Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis

The inflammatory response to Mycobacterium tuberculosis (M.tb) at the site of disease is Th1 driven. Whether the Th17 cytokines, IL-17 and IL-22, contribute to this response in humans is unknown. We hypothesized that IL-17 and IL-22 contribute to the inflammatory response in pleural and pericardial...

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Hauptverfasser: Matthews, Kerryn, Wilkinson, Katalin A., Kalsdorf, Barbara, Roberts, Teri, Diacon, Andreas, Walzl, Gerhard, Wolske, Janine, Ntsekhe, Mpiko, Syed, Faisal, Russell, James, Mayosi, Bongani M., Dawson, Rodney, Dheda, Keertan, Wilkinson, Robert J., Hanekom, Willem A., Scriba, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Churchill Livingstone 2011
Schlagworte:
Immunological Aspects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220762/
https://ncbi.nlm.nih.gov/pubmed/21767990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.06.009
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