Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis

The inflammatory response to Mycobacterium tuberculosis (M.tb) at the site of disease is Th1 driven. Whether the Th17 cytokines, IL-17 and IL-22, contribute to this response in humans is unknown. We hypothesized that IL-17 and IL-22 contribute to the inflammatory response in pleural and pericardial...

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Autors principals: Matthews, Kerryn, Wilkinson, Katalin A., Kalsdorf, Barbara, Roberts, Teri, Diacon, Andreas, Walzl, Gerhard, Wolske, Janine, Ntsekhe, Mpiko, Syed, Faisal, Russell, James, Mayosi, Bongani M., Dawson, Rodney, Dheda, Keertan, Wilkinson, Robert J., Hanekom, Willem A., Scriba, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Churchill Livingstone 2011
Matèries:
Immunological Aspects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220762/
https://ncbi.nlm.nih.gov/pubmed/21767990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.06.009
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