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Isotopic Signature Transfer and Mass Pattern Prediction (IsoStamp): An Enabling Technique for Chemically-Directed Proteomics

[Image: see text] Directed proteomics applies mass spectrometry analysis to a subset of information-rich proteins. Here we describe a method for targeting select proteins by chemical modification with a tag that imparts a distinct isotopic signature detectable in a full-scan mass spectrum. Termed is...

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Bibliografiske detaljer
Main Authors: Palaniappan, Krishnan K., Pitcher, Austin A., Smart, Brian P., Spiciarich, David R., Iavarone, Anthony T., Bertozzi, Carolyn R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220624/
https://ncbi.nlm.nih.gov/pubmed/21604797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100338x
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