Myotonic Dystrophy Protein Kinase Is Critical for Nuclear Envelope Integrity

Myotonic dystrophy 1 (DM1) is a multisystemic disease caused by a triplet nucleotide repeat expansion in the 3′ untranslated region of the gene coding for myotonic dystrophy protein kinase (DMPK). DMPK is a nuclear envelope (NE) protein that promotes myogenic gene expression in skeletal myoblasts. M...

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Bibliografiske detaljer
Main Authors: Harmon, Erin B., Harmon, Michelle L., Larsen, Tricia D., Yang, Jie, Glasford, Joseph W., Perryman, M. Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220565/
https://ncbi.nlm.nih.gov/pubmed/21949239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241455
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