Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN

Modification of the primary anchor positions of antigenic peptides to improve binding to major histocompatibility complex (MHC) proteins is a commonly used strategy for engineering peptide-based vaccine candidates. However, such peptide modifications do not always improve antigenicity, complicating...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Insaidoo, Francis K., Borbulevych, Oleg Y., Hossain, Moushumi, Santhanagopolan, Sujatha M., Baxter, Tiffany K., Baker, Brian M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
Immunology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220536/
https://ncbi.nlm.nih.gov/pubmed/21937447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.283564
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים