Genetic Dissection of the Functions of the Melanocortin-3 Receptor, a Seven-transmembrane G-protein-coupled Receptor, Suggests Roles for Central and Peripheral Receptors in Energy Homeostasis

The melanocortin-3 receptor (MC3R) gene is pleiotropic, influencing body composition, natriuresis, immune function, and entrainment of circadian rhythms to nutrient intake. MC3Rs are expressed in hypothalamic and limbic regions of the brain and in peripheral tissues. To investigate the roles of cent...

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Détails bibliographiques
Auteurs principaux: Begriche, Karima, Levasseur, Peter R., Zhang, Jingying, Rossi, Jari, Skorupa, Danielle, Solt, Laura A., Young, Brandon, Burris, Thomas P., Marks, Daniel L., Mynatt, Randall L., Butler, Andrew A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Metabolism
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220494/
https://ncbi.nlm.nih.gov/pubmed/21984834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.278374
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