C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake

Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake. However, the extracellular loop of SR-BI is large: it c...

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Bibliographic Details
Main Authors: Guo, Ling, Chen, Min, Song, Zhiqing, Daugherty, Alan, Li, Xiang-An
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220294/
https://ncbi.nlm.nih.gov/pubmed/21917726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019091
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