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Multidrug resistance P-glycoprotein dampens SR-BI cholesteryl ester uptake from high density lipoproteins in human leukemia cells

Tumor cells are characterised by a high content of cholesterol esters (CEs), while tumor-bearing patients show low levels of high-density lipoproteins (HDLs). The origin and significance of high CE levels in cancer cell biology has not been completely clarified. Recent evidence that lymphoblastic ce...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Spolitu, Stefano, Uda, Sabrina, Deligia, Stefania, Frau, Alessandra, Collu, Maria, Angius, Fabrizio, Batetta, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851841/
https://ncbi.nlm.nih.gov/pubmed/27152239
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