Influence of Hyperinsulinemia and Insulin Resistance on In Vivo β-Cell Function: Their Role in Human β-Cell Dysfunction

OBJECTIVE: Recent work has shown that insulin stimulates its own secretion in insulin-sensitive humans, suggesting that insulin resistance in the β-cell could cause β-cell dysfunction. We have tested whether insulin exposure and insulin sensitivity modulate β-cell function in subjects with normal gl...

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Detalles Bibliográficos
Main Authors: Mari, Andrea, Tura, Andrea, Natali, Andrea, Anderwald, Christian, Balkau, Beverley, Lalic, Nebojsa, Walker, Mark, Ferrannini, Ele
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2011
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219936/
https://ncbi.nlm.nih.gov/pubmed/22028180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0827
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