Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection

Following infection of the central nervous system (CNS), the immune system is faced with the challenge of eliminating the pathogen without causing significant damage to neurons, which have limited capacities of renewal. In particular, it was thought that neurons were protected from direct attack by...

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Detalhes bibliográficos
Main Authors: Chevalier, Grégoire, Suberbielle, Elsa, Monnet, Céline, Duplan, Valérie, Martin-Blondel, Guillaume, Farrugia, Fanny, Le Masson, Gwendal, Liblau, Roland, Gonzalez-Dunia, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219726/
https://ncbi.nlm.nih.gov/pubmed/22114563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002393
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