Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection

Following infection of the central nervous system (CNS), the immune system is faced with the challenge of eliminating the pathogen without causing significant damage to neurons, which have limited capacities of renewal. In particular, it was thought that neurons were protected from direct attack by...

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Autori principali: Chevalier, Grégoire, Suberbielle, Elsa, Monnet, Céline, Duplan, Valérie, Martin-Blondel, Guillaume, Farrugia, Fanny, Le Masson, Gwendal, Liblau, Roland, Gonzalez-Dunia, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219726/
https://ncbi.nlm.nih.gov/pubmed/22114563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002393
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