Nalaganje...
The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion
Long interspersed (L1) and Alu elements are actively amplified in the human genome through retrotransposition of their RNA intermediates by the ∼100 still retrotranspositionally fully competent L1 elements. Retrotransposition can cause inherited disease if such an element is inserted near or within...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219598/ https://ncbi.nlm.nih.gov/pubmed/22125493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002371 |
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